mTOR Is Essential for the Proteotoxic Stress Response, HSF1 Activation and Heat Shock Protein Synthesis

The target of rapamycin (TOR) is a high molecular weight protein kinase that regulates many processes in cells in response to mitogens and variations in nutrient availability. Here we have shown that mTOR in human tissue culture cells plays a key role in responses to proteotoxic stress and that redu...

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Detalles Bibliográficos
Autores principales: Chou, Shiuh-Dih, Prince, Thomas, Gong, Jianlin, Calderwood, Stuart K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387249/
https://www.ncbi.nlm.nih.gov/pubmed/22768106
http://dx.doi.org/10.1371/journal.pone.0039679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387249/
https://www.ncbi.nlm.nih.gov/pubmed/22768106
http://dx.doi.org/10.1371/journal.pone.0039679

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