Cargando…

Enhanced Membrane Pore Formation through High-Affinity Targeted Antimicrobial Peptides

Many cationic antimicrobial peptides (AMPs) target the unique lipid composition of the prokaryotic cell membrane. However, the micromolar activities common for these peptides are considered weak in comparison to nisin, which follows a targeted, pore-forming mode of action. Here we show that AMPs can...

Descripción completa

Detalles Bibliográficos
Autores principales: Arnusch, Christopher J., Pieters, Roland J., Breukink, Eefjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387250/
https://www.ncbi.nlm.nih.gov/pubmed/22768121
http://dx.doi.org/10.1371/journal.pone.0039768