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Vessel-Associated Transforming Growth Factor-Beta1 (TGF-β1) Is Increased in the Bronchial Reticular Basement Membrane in COPD and Normal Smokers

BACKGROUND: Transforming growth factor-beta1 (TGF-β1) is a multipotential cytokine with angiogenic activity. There are only limited data about its role in airway remodeling in COPD. We have previously shown that the reticular basement membrane (Rbm) is hypervascular in the airways of current smokers...

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Detalles Bibliográficos
Autores principales: Soltani, Amir, Sohal, Sukhwinder Singh, Reid, David, Weston, Steve, Wood-Baker, Richard, Walters, E. Haydn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387255/
https://www.ncbi.nlm.nih.gov/pubmed/22768115
http://dx.doi.org/10.1371/journal.pone.0039736