Cargando…

Vessel-Associated Transforming Growth Factor-Beta1 (TGF-β1) Is Increased in the Bronchial Reticular Basement Membrane in COPD and Normal Smokers

BACKGROUND: Transforming growth factor-beta1 (TGF-β1) is a multipotential cytokine with angiogenic activity. There are only limited data about its role in airway remodeling in COPD. We have previously shown that the reticular basement membrane (Rbm) is hypervascular in the airways of current smokers...

Descripción completa

Detalles Bibliográficos
Autores principales:	Soltani, Amir, Sohal, Sukhwinder Singh, Reid, David, Weston, Steve, Wood-Baker, Richard, Walters, E. Haydn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387255/ https://www.ncbi.nlm.nih.gov/pubmed/22768115 http://dx.doi.org/10.1371/journal.pone.0039736

Ejemplares similares

Distinctive characteristics of bronchial reticular basement membrane and vessel remodelling in chronic obstructive pulmonary disease (COPD) and in asthma: they are not the same disease
por: Soltani, Amir, et al.
Publicado: (2012)

Reticular Basement Membrane Vessels Are Increased in COPD Bronchial Mucosa by Both Factor VIII and Collagen IV Immunostaining and Are Hyperpermeable
por: Soltani, Amir, et al.
Publicado: (2012)

Basement membrane and vascular remodelling in smokers and chronic obstructive pulmonary disease: a cross-sectional study
por: Soltani, Amir, et al.
Publicado: (2010)

Changes in Airway Histone Deacetylase2 in Smokers and COPD with Inhaled Corticosteroids: A Randomized Controlled Trial
por: Sohal, Sukhwinder Singh, et al.
Publicado: (2013)

β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction
por: Mahmood, Malik Quasir, et al.
Publicado: (2017)

Epithelial mesenchymal transition (EMT) in small airways of COPD patients
por: Sohal, Sukhwinder Singh, et al.
Publicado: (2013)

Evaluation of epithelial mesenchymal transition in patients with chronic obstructive pulmonary disease
por: Sohal, Sukhwinder S, et al.
Publicado: (2011)

Role of epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD)
por: Sohal, Sukhwinder Singh, et al.
Publicado: (2013)

The main rhinovirus respiratory tract adhesion site (ICAM-1) is upregulated in smokers and patients with chronic airflow limitation (CAL)
por: Shukla, Shakti Dhar, et al.
Publicado: (2017)

Essential need for rethink of COPD airway pathology: implications for new drug approaches for prevention of lung cancer as well as small airway fibrosis
por: Sohal, Sukhwinder Singh, et al.
Publicado: (2017)

Inhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD
por: Soltani, Amir, et al.
Publicado: (2016)

A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial–mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study
por: Sohal, Sukhwinder Singh, et al.
Publicado: (2014)

Reticular basement membrane in asthma and COPD: Similar thickness, yet different composition
por: Liesker, Jeroen JW, et al.
Publicado: (2009)

Assessment of airway inflammation using sputum, BAL, and endobronchial biopsies in current and ex-smokers with established COPD
por: Wen, Yudong, et al.
Publicado: (2010)

Clinical significance of epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD): potential target for prevention of airway fibrosis and lung cancer
por: Sohal, Sukhwinder Singh, et al.
Publicado: (2014)

Increased myofibroblasts in the small airways, and relationship to remodelling and functional changes in smokers and COPD patients: potential role of epithelial–mesenchymal transition
por: Eapen, Mathew Suji, et al.
Publicado: (2021)

Relationship between blood and bronchial submucosal eosinophilia and reticular basement membrane thickening in chronic obstructive pulmonary disease
por: Eltboli, Osama, et al.
Publicado: (2015)

Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)
por: Eapen, Mathew Suji, et al.
Publicado: (2017)

Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction
por: Mahmood, Malik Quasir, et al.
Publicado: (2015)

Dotted Vessels in a Reticular Arrangement
por: Delli, Florentina Silvia, et al.
Publicado: (2022)

Estimation of TGF-β1 genotypes in Egyptian smokers; association with FEV(1) in COPD patients
por: Bohy, Mohammad El, et al.
Publicado: (2010)

Fluticasone propionate and increased risk of pneumonia in COPD: is it PAFR-dependent?
por: Sohal, Sukhwinder Singh
Publicado: (2017)

Clinical diaries in COPD: compliance and utility in predicting acute exacerbations
por: Walters, E Haydn, et al.
Publicado: (2012)

Therapeutic Modalities for Asthma, COPD, and Pathogenesis of COVID-19: Insights from the Special Issue
por: Sohal, Sukhwinder Singh
Publicado: (2022)

Endothelial to mesenchymal transition (EndMT): an active process in Chronic Obstructive Pulmonary Disease (COPD)?
por: Sohal, Sukhwinder Singh
Publicado: (2016)

Airway epithelial platelet-activating factor receptor expression is markedly upregulated in chronic obstructive pulmonary disease
por: Shukla, Shakti Dhar, et al.
Publicado: (2014)

Chronic Obstructive Pulmonary Disease (COPD) and Lung Cancer: Epithelial Mesenchymal Transition (EMT), the Missing Link?
por: Sohal, Sukhwinder Singh
Publicado: (2015)

Tissue fibrocytes in patients with mild asthma: A possible link to thickness of reticular basement membrane?
por: Nihlberg, Kristian, et al.
Publicado: (2006)

Transforming growth factor-β1 and SMAD signalling pathway in the small airways of smokers and patients with COPD: potential role in driving fibrotic type-2 epithelial mesenchymal transition
por: Brake, Samuel James, et al.
Publicado: (2023)

Albuterol enantiomer levels, lung function and QTc interval in patients with acute severe asthma and COPD in the emergency department
por: Yee, Kwang Choon, et al.
Publicado: (2011)

A randomized controlled trial of telephone-mentoring with home-based walking preceding rehabilitation in COPD
por: Cameron-Tucker, Helen Laura, et al.
Publicado: (2016)

Reticular Basement Membrane Thickness Is Associated with Growth- and Fibrosis-Promoting Airway Transcriptome Profile-Study in Asthma Patients
por: Bazan-Socha, Stanislawa, et al.
Publicado: (2021)

WNT/β-catenin pathway: A novel therapeutic target for attenuating airway remodelling and EMT in COPD
por: Eapen, Mathew Suji, et al.
Publicado: (2020)

Arterial remodelling in smokers and in patients with small airway disease and COPD: implications for lung physiology and early origins of pulmonary hypertension
por: Bhattarai, Prem, et al.
Publicado: (2022)

Chronic disease self-management and exercise in COPD as pulmonary rehabilitation: a randomized controlled trial
por: Cameron-Tucker, Helen L, et al.
Publicado: (2014)

Blocking rhinoviral adhesion molecule (ICAM-1): potential to prevent COPD exacerbations
por: Shukla, Shakti Dhar, et al.
Publicado: (2017)

AGER expression and alternative splicing in bronchial biopsies of smokers and never smokers
por: Faiz, Alen, et al.
Publicado: (2019)

Basement membrane regeneration and TGF-β1 expression in rabbits with corneal perforating injury
por: Meng, Na, et al.
Publicado: (2023)

The effect of multiple outgrowths from bronchial tissue explants on progenitor/stem cell number in primary bronchial epithelial cell cultures from smokers and patients with COPD
por: Bostancieri, Nuray, et al.
Publicado: (2023)

Monocyte chemotaxis in bronchial carcinoma and cigarette smokers.
por: Kay, A. B., et al.
Publicado: (1977)

Cannot write session to /tmp/vufind_sessions/sess_0dcq0fc49f9ken213cc2f1eklr