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Mitoxantrone Induces Natural Killer Cell Maturation in Patients with Secondary Progressive Multiple Sclerosis

Mitoxantrone is one of the few drugs approved for the treatment of progressive multiple sclerosis (MS). However, the prolonged use of this potent immunosuppressive agent is limited by the appearance of severe side effects. Apart from its general cytotoxic effect, the mode of action of mitoxantrone o...

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Detalles Bibliográficos
Autores principales: Chanvillard, Coralie, Millward, Jason M., Lozano, Marta, Hamann, Isabell, Paul, Friedemann, Zipp, Frauke, Dörr, Jan, Infante-Duarte, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387260/
https://www.ncbi.nlm.nih.gov/pubmed/22768101
http://dx.doi.org/10.1371/journal.pone.0039625