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6-Shogaol Induces Apoptosis in Human Hepatocellular Carcinoma Cells and Exhibits Anti-Tumor Activity In Vivo through Endoplasmic Reticulum Stress

6-Shogaol is an active compound isolated from Ginger (Zingiber officinale Rosc). In this work, we demonstrated that 6-shogaol induces apoptosis in human hepatocellular carcinoma cells in relation to caspase activation and endoplasmic reticulum (ER) stress signaling. Proteomic analysis revealed that...

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Detalles Bibliográficos
Autores principales: Hu, Rong, Zhou, Ping, Peng, Yong-Bo, Xu, Xiaojun, Ma, Jiang, Liu, Qun, Zhang, Lei, Wen, Xiao-Dong, Qi, Lian-Wen, Gao, Ning, Li, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387266/
https://www.ncbi.nlm.nih.gov/pubmed/22768104
http://dx.doi.org/10.1371/journal.pone.0039664