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Differential Activation of the ER Stress Factor XBP1 by Oligomeric Assemblies

Several neurodegenerative disorders are characterized by protein misfolding, a phenomenon that results in perturbation of cellular homeostasis. We recently identified the protective activity of the ER stress response factor XBP1 (X-box binding protein 1) against Amyloid-ß1-42 (Aß42) neurotoxicity in...

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Detalles Bibliográficos
Autores principales: Castillo-Carranza, Diana L., Zhang, Yan, Guerrero-Muñoz, Marcos J., Kayed, Rakez, Rincon-Limas, Diego E., Fernandez-Funez, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387497/
https://www.ncbi.nlm.nih.gov/pubmed/22528838
http://dx.doi.org/10.1007/s11064-012-0780-7