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Genetic variation in Hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are encoded by four genes (HCN1–4) and, through activation by cyclic AMP (cAMP), represent a point of convergence for several psychosis risk genes. On the basis of positive preliminary data, we sought to test whether genetic variatio...

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Detalles Bibliográficos
Autores principales: McIntosh, Andrew M., Simen, Arthur A., Evans, Kathryn L., Hall, Jeremy, MacIntyre, Donald J., Blackwood, Douglas, Morris, Andrew D., Smith, Blair H., Dominiczak, Anna, Porteous, David, Deary, hb Ian J., Thomson, Pippa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387669/
https://www.ncbi.nlm.nih.gov/pubmed/22783272
http://dx.doi.org/10.3389/fgene.2012.00116