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Genetic variation in Hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are encoded by four genes (HCN1–4) and, through activation by cyclic AMP (cAMP), represent a point of convergence for several psychosis risk genes. On the basis of positive preliminary data, we sought to test whether genetic variatio...
Autores principales: | McIntosh, Andrew M., Simen, Arthur A., Evans, Kathryn L., Hall, Jeremy, MacIntyre, Donald J., Blackwood, Douglas, Morris, Andrew D., Smith, Blair H., Dominiczak, Anna, Porteous, David, Deary, hb Ian J., Thomson, Pippa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387669/ https://www.ncbi.nlm.nih.gov/pubmed/22783272 http://dx.doi.org/10.3389/fgene.2012.00116 |
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