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miR-34 – a microRNA replacement therapy is headed to the clinic
MicroRNA-34 (miR-34) is a master regulator of tumor suppression. It is downregulated in numerous cancers and inhibits malignant growth by repressing genes involved in various oncogenic signaling pathways. Consequently, miR-34 antagonizes processes that are necessary for basic cancer cell viability a...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387671/ https://www.ncbi.nlm.nih.gov/pubmed/22783274 http://dx.doi.org/10.3389/fgene.2012.00120 |