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Funny Current and Cardiac Rhythm: Insights from HCN Knockout and Transgenic Mouse Models
In the adult animal the sinoatrial node (SAN) rhythmically generates a depolarizing wave that propagates to the rest of the heart. However, the SAN is more than a simple clock; it is a clock that adjusts its pace according to the metabolic requirements of the organism. The Hyperpolarization-activate...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387723/ https://www.ncbi.nlm.nih.gov/pubmed/22783204 http://dx.doi.org/10.3389/fphys.2012.00240 |