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Synthesis of two SAPAP3 isoforms from a single mRNA is mediated via alternative translational initiation

In mammalian neurons, targeting and translation of specific mRNAs in dendrites contribute to synaptic plasticity. After nuclear export, mRNAs designated for dendritic transport are generally assumed to be translationally dormant and activity of individual synapses may locally trigger their extrasoma...

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Detalles Bibliográficos
Autores principales: Chua, John Jia En, Schob, Claudia, Rehbein, Monika, Gkogkas, Christos G., Richter, Dietmar, Kindler, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387777/
https://www.ncbi.nlm.nih.gov/pubmed/22761992
http://dx.doi.org/10.1038/srep00484