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Synthesis of two SAPAP3 isoforms from a single mRNA is mediated via alternative translational initiation
In mammalian neurons, targeting and translation of specific mRNAs in dendrites contribute to synaptic plasticity. After nuclear export, mRNAs designated for dendritic transport are generally assumed to be translationally dormant and activity of individual synapses may locally trigger their extrasoma...
Autores principales: | Chua, John Jia En, Schob, Claudia, Rehbein, Monika, Gkogkas, Christos G., Richter, Dietmar, Kindler, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387777/ https://www.ncbi.nlm.nih.gov/pubmed/22761992 http://dx.doi.org/10.1038/srep00484 |
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