Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer’s disease

BACKGROUND: Microglial activation is an important histologic characteristic of the pathology of Alzheimer’s disease (AD). One hypothesis is that amyloid beta (Aβ) peptide serves as a specific stimulus for tyrosine kinase-based microglial activation leading to pro-inflammatory changes that contribute...

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Detalles Bibliográficos
Autores principales: Dhawan, Gunjan, Combs, Colin K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388011/
https://www.ncbi.nlm.nih.gov/pubmed/22673542
http://dx.doi.org/10.1186/1742-2094-9-117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388011/
https://www.ncbi.nlm.nih.gov/pubmed/22673542
http://dx.doi.org/10.1186/1742-2094-9-117

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