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Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer’s disease

BACKGROUND: Microglial activation is an important histologic characteristic of the pathology of Alzheimer’s disease (AD). One hypothesis is that amyloid beta (Aβ) peptide serves as a specific stimulus for tyrosine kinase-based microglial activation leading to pro-inflammatory changes that contribute...

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Detalles Bibliográficos
Autores principales:	Dhawan, Gunjan, Combs, Colin K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388011/ https://www.ncbi.nlm.nih.gov/pubmed/22673542 http://dx.doi.org/10.1186/1742-2094-9-117

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