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Activating KIR and HLA Bw4 Ligands Are Associated to Decreased Susceptibility to Pemphigus Foliaceus, an Autoimmune Blistering Skin Disease

The KIR genes and their HLA class I ligands have thus far not been investigated in pemphigus foliaceus (PF) and related autoimmune diseases, such as pemphigus vulgaris. We genotyped 233 patients and 204 controls for KIR by PCR-SSP. HLA typing was performed by LABType SSO reagent kits. We estimated t...

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Detalles Bibliográficos
Autores principales: Augusto, Danillo G., Lobo-Alves, Sara C., Melo, Marcia F., Pereira, Noemi F., Petzl-Erler, Maria Luiza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388041/
https://www.ncbi.nlm.nih.gov/pubmed/22768326
http://dx.doi.org/10.1371/journal.pone.0039991