Ferritin Blocks Inhibitory Effects of Two-Chain High Molecular Weight Kininogen (HKa) on Adhesion and Survival Signaling in Endothelial Cells

Angiogenesis is tightly regulated through complex crosstalk between pro- and anti-angiogenic signals. High molecular weight kininogen (HK) is an endogenous protein that is proteolytically cleaved in plasma and on endothelial cell surfaces to HKa, an anti-angiogenic protein. Ferritin binds to HKa and...

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Detalles Bibliográficos
Autores principales: Tesfay, Lia, Huhn, Annissa J., Hatcher, Heather, Torti, Frank M., Torti, Suzy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388046/
https://www.ncbi.nlm.nih.gov/pubmed/22768328
http://dx.doi.org/10.1371/journal.pone.0040030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388046/
https://www.ncbi.nlm.nih.gov/pubmed/22768328
http://dx.doi.org/10.1371/journal.pone.0040030

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