A Pro-Cathepsin L Mutant Is a Luminal Substrate for Endoplasmic-Reticulum-Associated Degradation in C. elegans

Endoplasmic-reticulum associated degradation (ERAD) is a major cellular misfolded protein disposal pathway that is well conserved from yeast to mammals. In yeast, a mutant of carboxypeptidase Y (CPY*) was found to be a luminal ER substrate and has served as a useful marker to help identify modifiers...

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Detalles Bibliográficos
Autores principales: Miedel, Mark T., Graf, Nathan J., Stephen, Kate E., Long, Olivia S., Pak, Stephen C., Perlmutter, David H., Silverman, Gary A., Luke, Cliff J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388072/
https://www.ncbi.nlm.nih.gov/pubmed/22768338
http://dx.doi.org/10.1371/journal.pone.0040145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388072/
https://www.ncbi.nlm.nih.gov/pubmed/22768338
http://dx.doi.org/10.1371/journal.pone.0040145

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