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Mathematical Models of E-Antigen Mediated Immune Tolerance and Activation following Prenatal HBV Infection
We develop mathematical models for the role of hepatitis B e-antigen in creating immunological tolerance during hepatitis B virus infection and propose mechanisms for hepatitis B e-antigen clearance, subsequent emergence of a potent cellular immune response, and the effect of these on liver damage....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388102/ https://www.ncbi.nlm.nih.gov/pubmed/22768303 http://dx.doi.org/10.1371/journal.pone.0039591 |