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Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53(+/−) mice and c-myc-3'RR/Cdk4(R24C) mice: differential oncogenic mechanisms but similar cellular origin

Mantle cell lymphoma (MCL) is a malignant lymphoproliferative B-cell disorder that does not occur spontaneously in mice but experimental mice model have been developed. Recently two different mice models prone to develop MCL-like lymphomas were generated: c-myc-3'RR/Cdk4(R24C) mice and c-myc-3&...

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Detalles Bibliográficos
Autores principales: Rouaud, Pauline, Fiancette, Rémi, Vincent-Fabert, Christelle, Magnone, Virginie, Cogné, Michel, Dubus, Pierre, Denizot, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388189/
https://www.ncbi.nlm.nih.gov/pubmed/22592113