TRAIL death receptors DR4 and DR5 mediate cerebral microvascular endothelial cell apoptosis induced by oligomeric Alzheimer's Aβ

Vascular deposition of amyloid-β (Aβ) in sporadic and familial Alzheimer's disease, through poorly understood molecular mechanisms, leads to focal ischemia, alterations in cerebral blood flow, and cerebral micro-/macro-hemorrhages, significantly contributing to cognitive impairment. Here, we sh...

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Detalles Bibliográficos
Autores principales: Fossati, S, Ghiso, J, Rostagno, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388229/
https://www.ncbi.nlm.nih.gov/pubmed/22695614
http://dx.doi.org/10.1038/cddis.2012.55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388229/
https://www.ncbi.nlm.nih.gov/pubmed/22695614
http://dx.doi.org/10.1038/cddis.2012.55

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