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Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts

3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors (statins) are cholesterol-lowering drugs that exert other cellular effects and underlie their beneficial health effects, including those associated with myocardial remodeling. We recently demonstrated that statins induces apoptosis and autophagy i...

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Detalles Bibliográficos
Autores principales: Ghavami, S, Yeganeh, B, Stelmack, G L, Kashani, H H, Sharma, P, Cunnington, R, Rattan, S, Bathe, K, Klonisch, T, Dixon, I M C, Freed, D H, Halayko, A J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388233/
https://www.ncbi.nlm.nih.gov/pubmed/22717585
http://dx.doi.org/10.1038/cddis.2012.61