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Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts
3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitors (statins) are cholesterol-lowering drugs that exert other cellular effects and underlie their beneficial health effects, including those associated with myocardial remodeling. We recently demonstrated that statins induces apoptosis and autophagy i...
Autores principales: | Ghavami, S, Yeganeh, B, Stelmack, G L, Kashani, H H, Sharma, P, Cunnington, R, Rattan, S, Bathe, K, Klonisch, T, Dixon, I M C, Freed, D H, Halayko, A J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388233/ https://www.ncbi.nlm.nih.gov/pubmed/22717585 http://dx.doi.org/10.1038/cddis.2012.61 |
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