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Anti-apoptotic effects of suppressor of cytokine signaling 3 and 1 in psoriasis

Because of their genetically determined capacity to respond to pro-inflammatory stimuli, keratinocytes have a crucial role in the pathogenesis of psoriasis. Upon IFN-γ and TNF-α exposure, psoriatic keratinocytes express exaggerated levels of inflammatory mediators, and show aberrant hyperproliferati...

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Detalles Bibliográficos
Autores principales: Madonna, S, Scarponi, C, Pallotta, S, Cavani, A, Albanesi, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388239/
https://www.ncbi.nlm.nih.gov/pubmed/22739986
http://dx.doi.org/10.1038/cddis.2012.69