HIV-1 Reverse Transcriptase Still Remains a New Drug Target: Structure, Function, Classical Inhibitors, and New Inhibitors with Innovative Mechanisms of Actions

During the retrotranscription process, characteristic of all retroviruses, the viral ssRNA genome is converted into integration-competent dsDNA. This process is accomplished by the virus-coded reverse transcriptase (RT) protein, which is a primary target in the current treatments for HIV-1 infection...

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Detalles Bibliográficos
Autores principales: Esposito, Francesca, Corona, Angela, Tramontano, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388302/
https://www.ncbi.nlm.nih.gov/pubmed/22778958
http://dx.doi.org/10.1155/2012/586401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388302/
https://www.ncbi.nlm.nih.gov/pubmed/22778958
http://dx.doi.org/10.1155/2012/586401

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