Magnetic-Fe/Fe(3)O(4)-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages

The targeted delivery of therapeutics to the tumor site is highly desirable in cancer treatment, because it is capable of minimizing collateral damage. Herein, we report the synthesis of a nanoplatform, which is composed of a 15 ± 1 nm diameter core/shell Fe/Fe(3)O(4) magnetic nanoparticles (MNPs) a...

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Detalles Bibliográficos
Autores principales: Wang, Hongwang, Shrestha, Tej B, Basel, Matthew T, Dani, Raj Kumar, Seo, Gwi-Moon, Balivada, Sivasai, Pyle, Marla M, Prock, Heidy, Koper, Olga B, Thapa, Prem S, Moore, David, Li, Ping, Chikan, Viktor, Troyer, Deryl L, Bossmann, Stefan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388369/
https://www.ncbi.nlm.nih.gov/pubmed/23016149
http://dx.doi.org/10.3762/bjnano.3.51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388369/
https://www.ncbi.nlm.nih.gov/pubmed/23016149
http://dx.doi.org/10.3762/bjnano.3.51

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