PPARδ Activation Rescues Pancreatic β-Cell Line INS-1E from Palmitate-Induced Endoplasmic Reticulum Stress through Enhanced Fatty Acid Oxidation

One of the key factors responsible for the development of type 2 diabetes is the loss of functional pancreatic β cells. This occurs due to a chronic exposure to a high fatty acid environment. ER stress is caused by an accumulation of irreversible misfold or unfold protein: these trigger the death of...

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Detalles Bibliográficos
Autores principales: Cao, Mingming, Tong, Yuzhen, Lv, Qingguo, Chen, Xiang, Long, Yang, Jiang, Li, Wan, Jun, Zhang, Yuwei, Zhang, Fang, Tong, Nanwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388384/
https://www.ncbi.nlm.nih.gov/pubmed/22792088
http://dx.doi.org/10.1155/2012/680684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388384/
https://www.ncbi.nlm.nih.gov/pubmed/22792088
http://dx.doi.org/10.1155/2012/680684

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