Cargando…

PPARδ Activation Rescues Pancreatic β-Cell Line INS-1E from Palmitate-Induced Endoplasmic Reticulum Stress through Enhanced Fatty Acid Oxidation

One of the key factors responsible for the development of type 2 diabetes is the loss of functional pancreatic β cells. This occurs due to a chronic exposure to a high fatty acid environment. ER stress is caused by an accumulation of irreversible misfold or unfold protein: these trigger the death of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Mingming, Tong, Yuzhen, Lv, Qingguo, Chen, Xiang, Long, Yang, Jiang, Li, Wan, Jun, Zhang, Yuwei, Zhang, Fang, Tong, Nanwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388384/ https://www.ncbi.nlm.nih.gov/pubmed/22792088 http://dx.doi.org/10.1155/2012/680684

Ejemplares similares

Interleukin-22 Alleviated Palmitate-Induced Endoplasmic Reticulum Stress in INS-1 Cells through Activation of Autophagy
por: Hu, Minling, et al.
Publicado: (2016)

Procyanidin B2 mitigates endothelial endoplasmic reticulum stress through a PPARδ-Dependent mechanism
por: Nie, Xin, et al.
Publicado: (2020)

Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells
por: Hong, Seok-Woo, et al.
Publicado: (2018)

The association of hypernatremia and hypertonic saline irrigation in hepatic hydatid cysts: A case report and retrospective study
por: Zeng, Rujun, et al.
Publicado: (2017)

A Novel Nonsense INS Mutation Causes Inefficient Preproinsulin Translocation Into the Endoplasmic Reticulum
por: Yang, Ying, et al.
Publicado: (2022)

PPARδ attenuates hepatic steatosis through autophagy-mediated fatty acid oxidation
por: Tong, Lei, et al.
Publicado: (2019)

Chlorogenic acid against palmitic acid in endoplasmic reticulum stress-mediated apoptosis resulting in protective effect of primary rat hepatocytes
por: Zhang, Yong, et al.
Publicado: (2018)

Palmitate induces endoplasmic reticulum stress and autophagy in mature adipocytes: Implications for apoptosis and inflammation
por: YIN, JIAJING, et al.
Publicado: (2015)

Involvement of Endoplasmic Reticulum Stress in Palmitate-induced Apoptosis in HepG2 Cells
por: Cho, Hyang-Ki, et al.
Publicado: (2008)

A primary effect of palmitic acid on mouse oocytes is the disruption of the structure of the endoplasmic reticulum
por: Wang, Yisu, et al.
Publicado: (2021)

The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts
por: Yang, Hsiang-Yu, et al.
Publicado: (2022)

Glucagon-like peptide-1 mimetics, optimal for Asian type 2 diabetes patients with and without overweight/obesity: meta-analysis of randomized controlled trials
por: Zhang, Fang, et al.
Publicado: (2017)

Modified High-Sucrose Diet-Induced Abdominally Obese and Normal-Weight Rats Developed High Plasma Free Fatty Acid and Insulin Resistance
por: Cao, Li, et al.
Publicado: (2012)

Role of endoplasmic reticulum stress in the protective effects of PPARβ/δ activation on endothelial dysfunction induced by plasma from patients with lupus
por: Toral, Marta, et al.
Publicado: (2017)

Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death
por: Shibusawa, Ryo, et al.
Publicado: (2019)

Palmitate is not an effective fuel for pancreatic islets and amplifies insulin secretion independent of calcium release from endoplasmic reticulum
por: Kuok, Iok Teng, et al.
Publicado: (2019)

GRP75 mediates endoplasmic reticulum–mitochondria coupling during palmitate-induced pancreatic β-cell apoptosis
por: Tiwary, Shweta, et al.
Publicado: (2021)

Delivery of phosphatidylethanolamine blunts stress in hepatoma cells exposed to elevated palmitate by targeting the endoplasmic reticulum
por: Trentzsch, Marcus, et al.
Publicado: (2020)

Preoperative selective vs non-selective α-blockade in PPGL patients undergoing adrenalectomy
por: Liu, Caojie, et al.
Publicado: (2017)

The Effects of Glyburide on Apoptosis and Endoplasmic Reticulum Stress in INS-1 Cells in a Glucolipotoxic Condition
por: Kwon, Min Jeong, et al.
Publicado: (2011)

Changes of MODY signal pathway genes in the endoplasmic reticulum stress in INS-1-3 cells
por: Dong, Yanan, et al.
Publicado: (2018)

Plant Sterol Ester of α-Linolenic Acid Attenuates Nonalcoholic Fatty Liver Disease by Rescuing the Adaption to Endoplasmic Reticulum Stress and Enhancing Mitochondrial Biogenesis
por: Han, Hao, et al.
Publicado: (2019)

Endoplasmic reticulum stress response in an INS-1 pancreatic β-cell line with inducible expression of a folding-deficient proinsulin
por: Hartley, Taila, et al.
Publicado: (2010)

Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR
por: Sabirzhanova, Inna, et al.
Publicado: (2018)

DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia
por: Ding, Jie, et al.
Publicado: (2017)

Evidence From a Systematic Review and Meta-Analysis: Classical Impaired Glucose Tolerance Should Be Divided Into Subgroups of Isolated Impaired Glucose Tolerance and Impaired Glucose Tolerance Combined With Impaired Fasting Glucose, According to the Risk of Progression to Diabetes
por: Liu, Yupu, et al.
Publicado: (2022)

Melatonin attenuates palmitic acid-induced mouse granulosa cells apoptosis via endoplasmic reticulum stress
por: Chen, Zhi, et al.
Publicado: (2019)

Curcumin Alleviates Palmitic Acid-Induced LOX-1 Upregulation by Suppressing Endoplasmic Reticulum Stress in HUVECs
por: Luo, Ruixi, et al.
Publicado: (2021)

Liraglutide Counteracts Endoplasmic Reticulum Stress in Palmitate-Treated Hypothalamic Neurons without Restoring Mitochondrial Homeostasis
por: Griffin, Haven, et al.
Publicado: (2022)

Rescue of HSP70 in Spinal Neurons Alleviates Opioids-Induced Hyperalgesia via the Suppression of Endoplasmic Reticulum Stress in Rodents
por: Lin, Tong-Tong, et al.
Publicado: (2020)

Activating PPARβ/δ Protects against Endoplasmic Reticulum Stress-Induced Astrocytic Apoptosis via UCP2-Dependent Mitophagy in Depressive Model
por: Ji, Juan, et al.
Publicado: (2022)

Glucolipotoxicity Impairs Ceramide Flow from the Endoplasmic Reticulum to the Golgi Apparatus in INS-1 β-Cells
por: Gjoni, Enida, et al.
Publicado: (2014)

Endoplasmic reticulum stress induced by lipopolysaccharide is involved in the association between inflammation and autophagy in INS-1 cells
por: Liu, Han, et al.
Publicado: (2017)

Effect of α-linolenic acid on endoplasmic reticulum stress-mediated apoptosis of palmitic acid lipotoxicity in primary rat hepatocytes
por: Zhang, Yong, et al.
Publicado: (2011)

Curcumin Improves Palmitate-Induced Insulin Resistance in Human Umbilical Vein Endothelial Cells by Maintaining Proteostasis in Endoplasmic Reticulum
por: Ye, Mao, et al.
Publicado: (2017)

Endoplasmic Reticulum–Mitochondria Contact Sites and Neurodegeneration
por: Xu, Lingna, et al.
Publicado: (2020)

Oxidative and endoplasmic reticulum stresses are involved in palmitic acid-induced H9c2 cell apoptosis
por: Yang, Lei, et al.
Publicado: (2019)

Phlorotannins from Ecklonia cava Attenuates Palmitate-Induced Endoplasmic Reticulum Stress and Leptin Resistance in Hypothalamic Neurons
por: Oh, Seyeon, et al.
Publicado: (2019)

Endoplasmic reticulum stress in amelogenesis imperfecta and phenotypic rescue using 4-phenylbutyrate
por: Brookes, Steven J., et al.
Publicado: (2014)

Endoplasmic reticulum stress in human chronic wound healing: Rescue by 4‐phenylbutyrate
por: Bachar‐Wikstrom, Etty, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hvmo2kbv7vl5uke4e80b2jhh4i