C-Peptide Reduces Mitochondrial Superoxide Generation by Restoring Complex I Activity in High Glucose-Exposed Renal Microvascular Endothelial Cells

Hyperglycemia-mediated microvascular damage has been proposed to originate from excessive generation of mitochondrial superoxide in endothelial cells and is the suggested mechanism by which the pathogenesis of diabetes-induced renal damage occurs. C-peptide has been shown to ameliorate diabetes-indu...

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Detalles Bibliográficos
Autores principales: Vejandla, Himani, Hollander, John M., Kothur, Anand, Brock, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388427/
https://www.ncbi.nlm.nih.gov/pubmed/22778984
http://dx.doi.org/10.5402/2012/162802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388427/
https://www.ncbi.nlm.nih.gov/pubmed/22778984
http://dx.doi.org/10.5402/2012/162802

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