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Pathological Significance of Mitochondrial Glycation

Glycation, the nonenzymatic glycosylation of biomolecules, is commonly observed in diabetes and ageing. Reactive dicarbonyl species such as methylglyoxal and glyoxal are thought to be major physiological precursors of glycation. Because these dicarbonyls tend to be formed intracellularly, the levels...

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Detalles Bibliográficos
Autores principales: Pun, Pamela Boon Li, Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388455/
https://www.ncbi.nlm.nih.gov/pubmed/22778743
http://dx.doi.org/10.1155/2012/843505