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The CRKL gene encoding an adaptor protein is amplified, overexpressed, and a possible therapeutic target in gastric cancer

BACKGROUND: Genomic DNA amplification is a genetic factor involved in cancer, and some oncogenes, such as ERBB2, are highly amplified in gastric cancer. We searched for the possible amplification of other genes in gastric cancer. METHODS AND RESULTS: A genome-wide single nucleotide polymorphism micr...

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Detalles Bibliográficos
Autores principales: Natsume, Hiroko, Shinmura, Kazuya, Tao, Hong, Igarashi, Hisaki, Suzuki, Masaya, Nagura, Kiyoko, Goto, Masanori, Yamada, Hidetaka, Maeda, Matsuyoshi, Konno, Hiroyuki, Nakamura, Satoki, Sugimura, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388458/
https://www.ncbi.nlm.nih.gov/pubmed/22591714
http://dx.doi.org/10.1186/1479-5876-10-97