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A novel oncogenic pathway by TLS–CHOP involving repression of MDA-7/IL-24 expression

BACKGROUND: Translocated in liposarcoma-CCAAT/enhancer binding protein homologous protein (TLS–CHOP) (also known as FUS-DDIT3) chimeric oncoprotein is found in the majority of human myxoid liposarcoma (MLS), but its molecular function remains unclear. METHODS: We knockdowned TLS–CHOP expression in M...

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Detalles Bibliográficos
Autores principales: Oikawa, K, Tanaka, M, Itoh, S, Takanashi, M, Ozaki, T, Muragaki, Y, Kuroda, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388565/
https://www.ncbi.nlm.nih.gov/pubmed/22588557
http://dx.doi.org/10.1038/bjc.2012.199