In vitro analysis of ovarian cancer response to cisplatin, carboplatin, and paclitaxel identifies common pathways that are also associated with overall patient survival

BACKGROUND: Carboplatin and cisplatin, alone or in combination with paclitaxel, have similar efficacies against ovarian cancer (OVCA) yet exhibit different toxicity profiles. We characterised the common and unique cellular pathways that underlie OVCA response to these drugs and analyse whether they...

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Detalles Bibliográficos
Autores principales: Bicaku, E, Xiong, Y, Marchion, D C, Chon, H S, Stickles, X B, Chen, N, Judson, P L, Hakam, A, Gonzalez-Bosquet, J, Wenham, R M, Apte, S M, Fulp, W, Cubitt, C L, Chen, D-T, Lancaster, J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388569/
https://www.ncbi.nlm.nih.gov/pubmed/22596241
http://dx.doi.org/10.1038/bjc.2012.207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388569/
https://www.ncbi.nlm.nih.gov/pubmed/22596241
http://dx.doi.org/10.1038/bjc.2012.207

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