Cargando…
In vitro analysis of ovarian cancer response to cisplatin, carboplatin, and paclitaxel identifies common pathways that are also associated with overall patient survival
BACKGROUND: Carboplatin and cisplatin, alone or in combination with paclitaxel, have similar efficacies against ovarian cancer (OVCA) yet exhibit different toxicity profiles. We characterised the common and unique cellular pathways that underlie OVCA response to these drugs and analyse whether they...
Autores principales: | Bicaku, E, Xiong, Y, Marchion, D C, Chon, H S, Stickles, X B, Chen, N, Judson, P L, Hakam, A, Gonzalez-Bosquet, J, Wenham, R M, Apte, S M, Fulp, W, Cubitt, C L, Chen, D-T, Lancaster, J M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388569/ https://www.ncbi.nlm.nih.gov/pubmed/22596241 http://dx.doi.org/10.1038/bjc.2012.207 |
Ejemplares similares
-
A novel c-Met inhibitor, MK8033, synergizes with carboplatin plus paclitaxel to inhibit ovarian cancer cell growth
por: MARCHION, DOUGLAS C., et al.
Publicado: (2013) -
BCL2 antagonist of cell death kinases, phosphatases, and ovarian cancer sensitivity to cisplatin
por: Bansal, Nisha, et al.
Publicado: (2012) -
Human cancer cell line microRNAs associated with in vitro sensitivity to paclitaxel
por: CHEN, NING, et al.
Publicado: (2014) -
Kinase-driven metabolic signalling as a predictor of response to carboplatin–paclitaxel adjuvant treatment in advanced ovarian cancers
por: Sereni, Maria Isabella, et al.
Publicado: (2017) -
BAD-mediated apoptotic pathway is associated with human cancer development
por: STICKLES, XIAOMANG B, et al.
Publicado: (2015)