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False-negative MRI biomarkers of tumour response to targeted cancer therapeutics

BACKGROUND: Non-invasive quantitative imaging biomarkers are essential for the evaluation of novel targeted therapeutics. Before deployment in clinical trials, such imaging biomarkers require qualification, typically through pre-clinical identification of imaging-pathology correlates. METHODS: First...

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Detalles Bibliográficos
Autores principales: Boult, J K R, Jamin, Y, Jacobs, V, Gilmour, L D, Walker-Samuel, S, Halliday, J, Elvin, P, Ryan, A J, Waterton, J C, Robinson, S P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388570/
https://www.ncbi.nlm.nih.gov/pubmed/22596237
http://dx.doi.org/10.1038/bjc.2012.208