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An easily accessible sulfated saccharide mimetic inhibits in vitro human tumor cell adhesion and angiogenesis of vascular endothelial cells

Oligosaccharides aberrantly expressed on tumor cells influence processes such as cell adhesion and modulation of the cell’s microenvironment resulting in an increased malignancy. Schmidt’s imidate strategy offers an effective method to synthesize libraries of various oligosaccharide mimetics. With t...

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Detalles Bibliográficos
Autores principales: Marano, Grazia, Gronewold, Claas, Frank, Martin, Merling, Anette, Kliem, Christian, Sauer, Sandra, Wiessler, Manfred, Frei, Eva, Schwartz-Albiez, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388867/
https://www.ncbi.nlm.nih.gov/pubmed/23015827
http://dx.doi.org/10.3762/bjoc.8.89