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Unprecedented deoxygenation at C-7 of the ansamitocin core during mutasynthetic biotransformations
We describe the unprecedented formation of six ansamitocin derivatives that are deoxygenated at C-7 of the ansamitocin core, obtained during fermentation experiments by employing a variety of Actinosynnema pretiosum mutants and mutasynthetic approaches. We suggest that the formation of these derivat...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388874/ https://www.ncbi.nlm.nih.gov/pubmed/23015834 http://dx.doi.org/10.3762/bjoc.8.96 |