Cargando…

Unprecedented deoxygenation at C-7 of the ansamitocin core during mutasynthetic biotransformations

We describe the unprecedented formation of six ansamitocin derivatives that are deoxygenated at C-7 of the ansamitocin core, obtained during fermentation experiments by employing a variety of Actinosynnema pretiosum mutants and mutasynthetic approaches. We suggest that the formation of these derivat...

Descripción completa

Detalles Bibliográficos
Autores principales: Knobloch, Tobias, Dräger, Gerald, Collisi, Wera, Sasse, Florenz, Kirschning, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388874/
https://www.ncbi.nlm.nih.gov/pubmed/23015834
http://dx.doi.org/10.3762/bjoc.8.96