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Unprecedented deoxygenation at C-7 of the ansamitocin core during mutasynthetic biotransformations
We describe the unprecedented formation of six ansamitocin derivatives that are deoxygenated at C-7 of the ansamitocin core, obtained during fermentation experiments by employing a variety of Actinosynnema pretiosum mutants and mutasynthetic approaches. We suggest that the formation of these derivat...
Autores principales: | Knobloch, Tobias, Dräger, Gerald, Collisi, Wera, Sasse, Florenz, Kirschning, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388874/ https://www.ncbi.nlm.nih.gov/pubmed/23015834 http://dx.doi.org/10.3762/bjoc.8.96 |
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