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Low-generation dendrimers with a calixarene core and based on a chiral C(2)-symmetric pyrrolidine as iminosugar mimics

The preparation of low-generation dendrimers based on a simple calix[4]arene scaffold by insertion of the iminosugar-analogue C(2)-symmetric 3,4-dihydroxypyrrolidine is described. This methodology allows a rapid incorporation of a considerable number of iminosugar-like moieties in a reduced volume a...

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Detalles Bibliográficos
Autores principales: Marradi, Marco, Cicchi, Stefano, Sansone, Francesco, Casnati, Alessandro, Goti, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388885/
https://www.ncbi.nlm.nih.gov/pubmed/23015845
http://dx.doi.org/10.3762/bjoc.8.107