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IRS-2 Deficiency Impairs NMDA Receptor-Dependent Long-term Potentiation
The beneficial effects of insulin and insulin-like growth factor I on cognition have been documented in humans and animal models. Conversely, obesity, hyperinsulinemia, and diabetes increase the risk for neurodegenerative disorders including Alzheimer's disease (AD). However, the mechanisms by...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388895/ https://www.ncbi.nlm.nih.gov/pubmed/21955917 http://dx.doi.org/10.1093/cercor/bhr216 |