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IRS-2 Deficiency Impairs NMDA Receptor-Dependent Long-term Potentiation

The beneficial effects of insulin and insulin-like growth factor I on cognition have been documented in humans and animal models. Conversely, obesity, hyperinsulinemia, and diabetes increase the risk for neurodegenerative disorders including Alzheimer's disease (AD). However, the mechanisms by...

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Detalles Bibliográficos
Autores principales: Martín, Eduardo D., Sánchez-Perez, Ana, Trejo, José Luis, Martin-Aldana, Juan Antonio, Cano Jaimez, Marife, Pons, Sebastián, Acosta Umanzor, Carlos, Menes, Lorena, White, Morris F., Burks, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388895/
https://www.ncbi.nlm.nih.gov/pubmed/21955917
http://dx.doi.org/10.1093/cercor/bhr216