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Etanercept, a Widely Used Inhibitor of Tumor Necrosis Factor-α (TNF- α), Prevents Retinal Ganglion Cell Loss in a Rat Model of Glaucoma

BACKGROUND: Visual loss in glaucoma is associated with pathological changes in retinal ganglion cell (RGC) axons and a slow decline in the RGC population. Age and elevated intraocular pressure (IOP) are the main risk factors for glaucomatous loss of vision. Several studies have implicated the proinf...

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Detalles Bibliográficos
Autores principales: Roh, Miin, Zhang, Yan, Murakami, Yusuke, Thanos, Aristomenis, Lee, Sung Chul, Vavvas, Demetrios G., Benowitz, Larry I., Miller, Joan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388998/
https://www.ncbi.nlm.nih.gov/pubmed/22802951
http://dx.doi.org/10.1371/journal.pone.0040065