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Niche-Associated Activation of Rac Promotes the Asymmetric Division of Drosophila Female Germline Stem Cells
BACKGROUND: Drosophila female germline stem cells (GSCs) reside adjacent to a cellular niche that secretes Bone Morphogenetic Protein (BMP) ligands and anchors the GSCs through adherens junctions. The GSCs divide asymmetrically such that one daughter remains in the niche as a GSC, while the other is...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389017/ https://www.ncbi.nlm.nih.gov/pubmed/22802725 http://dx.doi.org/10.1371/journal.pbio.1001357 |