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Arsenic trioxide induces depolymerization of microtubules in an acute promyelocytic leukemia cell line

BACKGROUND: Arsenic trioxide (As(2)O(3)) is a well-known and effective treatment that can result in clinical remission for patients diagnosed with acute promyelocytic leukemia (APL). The biologic efficacy of As(2)O(3) in APL and solid tumor cells has been explained through its actions on anti-prolif...

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Detalles Bibliográficos
Autores principales: Baek, Jin Ho, Moon, Chang Hoon, Cha, Seung Joo, Lee, Hee Soon, Noh, Eui-Kyu, Kim, Hawk, Won, Jong-Ho, Min, Young Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389058/
https://www.ncbi.nlm.nih.gov/pubmed/22783356
http://dx.doi.org/10.5045/kjh.2012.47.2.105