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Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platforms
Several RNA viruses have recently been shown to hijack members of the host phosphatidylinositol (PtdIns) 4-kinase (PI4K) family of enzymes. They use PI4K to generate membranes enriched in phosphatidylinositide 4-phosphate (PtdIns4P or PI4P) lipids, which can be used as replication platforms. Viral r...
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Fformat: | Online Erthygl Texto |
Iaith: | English |
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Elsevier Ltd. Published by Elsevier Ltd.
2012
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Mynediad Ar-lein: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389303/ https://www.ncbi.nlm.nih.gov/pubmed/22633842 http://dx.doi.org/10.1016/j.tibs.2012.03.004 |