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O-GlcNAcylation and oxidation of proteins: is signalling in the cardiovascular system becoming sweeter?

O-GlcNAcylation is an unusual form of protein glycosylation, where a single-sugar [GlcNAc (N-acetylglucosamine)] is added (via β-attachment) to the hydroxyl moiety of serine and threonine residues of nuclear and cytoplasmic proteins. A complex and extensive interplay exists between O-GlcNAcylation a...

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Detalles Bibliográficos
Autores principales: Lima, Victor V., Spitler, Kathryn, Choi, Hyehun, Webb, R. Clinton, Tostes, Rita C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389386/
https://www.ncbi.nlm.nih.gov/pubmed/22757958
http://dx.doi.org/10.1042/CS20110638