Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo

BACKGROUND: The small stress heat shock protein 27 (Hsp27) has recently turned as a promising target for cancer treatment. Hsp27 upregulation is associated with tumour growth and resistance to chemo- and radio-therapeutic treatments, and several ongoing drugs inhibiting Hsp27 expression are under cl...

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Detalles Bibliográficos
Autores principales: Gibert, B, Eckel, B, Gonin, V, Goldschneider, D, Fombonne, J, Deux, B, Mehlen, P, Arrigo, A-P, Clézardin, P, Diaz-Latoud, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389402/
https://www.ncbi.nlm.nih.gov/pubmed/22627320
http://dx.doi.org/10.1038/bjc.2012.188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389402/
https://www.ncbi.nlm.nih.gov/pubmed/22627320
http://dx.doi.org/10.1038/bjc.2012.188

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