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Regulator of G-Protein Signaling 5 Reduces HeyA8 Ovarian Cancer Cell Proliferation and Extends Survival in a Murine Tumor Model

The regulator of G-protein signaling 5 (RGS5) belongs to a family of GTPase activators that terminate signaling cascades initiated by extracellular mediators and G-protein-coupled receptors. RGS5 has an interesting dual biological role. One functional RGS5 role is as a pericyte biomarker influencing...

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Detalles Bibliográficos
Autores principales: Altman, Molly K., Nguyen, Duy T., Patel, Santosh B., Fambrough, Jada M., Beedle, Aaron M., Hardman, William J., Murph, Mandi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389655/
https://www.ncbi.nlm.nih.gov/pubmed/22792465
http://dx.doi.org/10.1155/2012/518437