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Relative Copy Number Variations of CYP2C19 in South Indian Population

CYP2C19 is a polymorphic enzyme involved in the metabolism of clinically important drugs. Genotype-phenotype association studies of CYP2C19 have reported wide ranges in the metabolic ratios of its substrates. These discrepancies could be attributed to the variations in the promoter region and this a...

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Detalles Bibliográficos
Autores principales: Devendran, Anichavezhi, Uppugunduri, Chakradhara Rao Satyanarayana, Sundaram, Rajan, Shewade, Deepak Gopal, Rajagopal, Krishnamoorthy, Chandrasekaran, Adithan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389726/
https://www.ncbi.nlm.nih.gov/pubmed/22792463
http://dx.doi.org/10.1155/2012/643856