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Correcting for the bias due to expression specificity improves the estimation of constrained evolution of expression between mouse and human
Motivation: Comparative analyses of gene expression data from different species have become an important component of the study of molecular evolution. Thus methods are needed to estimate evolutionary distances between expression profiles, as well as a neutral reference to estimate selective pressur...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389764/ https://www.ncbi.nlm.nih.gov/pubmed/22576178 http://dx.doi.org/10.1093/bioinformatics/bts266 |