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Correcting for the bias due to expression specificity improves the estimation of constrained evolution of expression between mouse and human

Motivation: Comparative analyses of gene expression data from different species have become an important component of the study of molecular evolution. Thus methods are needed to estimate evolutionary distances between expression profiles, as well as a neutral reference to estimate selective pressur...

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Detalles Bibliográficos
Autores principales: Piasecka, Barbara, Robinson-Rechavi, Marc, Bergmann, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389764/
https://www.ncbi.nlm.nih.gov/pubmed/22576178
http://dx.doi.org/10.1093/bioinformatics/bts266